Trusted by Dr. Bernstein
Veterinarian
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Liquid collagen can't be mass-produced like cheap pills and chews — limited quantities available.
PS: We only sell through this official site — if you see it on Amazon or eBay, it's not us.
We offer a full 60-Day Money-Back Guarantee.
If you don't see real improvement in your dog's scratching, hot spots, ear infections, paw licking or coat within 60 days, simply email us and we'll happily sort out your refund.
We're confident because this addresses the root cause (broken skin barrier) — not just symptoms. But if it doesn't work for your dog, you don't pay.
Your dog's skin has a protective barrier made of collagen — and it's breaking down faster than you think.
Dogs lose 7-10% of their collagen every year after age 2. Genetics, chronic scratching, antibiotics, and poor diet can accelerate it even faster. That's why some 2 or 3-year-old dogs already have chronic skin issues.
As collagen depletes, gaps form. Allergens penetrate deep. The immune system goes into overdrive. That's the constant itching, hot spots, and scratching that never stops.
Apoquel and Cytopoint suppress symptoms — but they don't rebuild the barrier. That's why they fade.
Our formula rebuilds the barrier itself. All three collagen types (Types I, II & III) in liquid form for 98% absorption. Plus Omega 3 for fast itch relief and Vitamin C to help your dog's body turn that collagen into new, healthy skin tissue.
You're not masking symptoms. You're fixing the structure.
Mix into food once daily. Tasteless — dogs don't notice it.
Dosage by weight:
Your dog's barrier needs ongoing collagen to stay strong. If you stop, symptoms can return.
Not sure yet? Start with 1 bottle. 60-day money-back guarantee.
Most owners see the first change at 2 to 3 weeks: less night scratching, calmer skin, quieter paws. The first week or two can look like nothing is happening. That's normal; the barrier rebuilds from the inside before you see it on the outside.
Deeper problems like chronic hot spots, recurring ear infections or severe allergies usually take 6 to 8 weeks.
Itching, hot spots, ear infections, paw licking: all symptoms of the same broken barrier. As it rebuilds, they improve together. Owners tell us the coat comes back thicker, energy picks up, and their dog is sleeping through the night again.
Nothing at three weeks? Check the dose against the weight table and keep going to week six. No change at 60 days, and the guarantee means you don't pay.
Your dog loses collagen every year. Daily use keeps the barrier strong and the allergens out.
Hydrolyzed Marine Collagen (Types I & III) 900mg
The foundation of your dog's skin barrier. Type I rebuilds the protective barrier that keeps allergens out. Type III repairs damaged tissue and heals hot spots, raw patches, and scratched areas. Hydrolyzed means it's already broken down small enough to absorb, instead of being digested like food.
UC-II (Type II Collagen) 40mg
Reduces systemic inflammation driving the constant itch response. Clinically studied dose proven to calm inflammatory pathways throughout the body.
Omega 3 400mg
Powerful anti-inflammatory that reduces itch and discomfort while collagen rebuilds the barrier. Provides fast relief during the repair process. The natural oils that seal the barrier, the mortar between the bricks. On its own, fish oil is mortar with no foundation underneath. Here it works alongside the collagen that rebuilds it.
Vitamin C 50mg
Essential for collagen synthesis. Helps your dog's body produce and repair collagen tissue effectively.
One serving on their food, once a day. Dogs think it's a treat, not medicine.
Is this right for my dog?
For dogs with chronic allergies who scratch constantly, have hot spots, recurring ear infections, paw licking, or thinning fur. If symptoms keep coming back no matter what you try — their skin barrier is breaking down and needs to be rebuilt.
Is It Safe? Can I give this with Apoquel or Cytopoint?
Yes. It's 100% natural, non-GMO, made in a GMP-certified facility and third-party tested. Safe for daily, long-term use and safe alongside all medications, including Apoquel, Cytopoint, Zenrelia, steroids, Benadryl, Zyrtec and antibiotics. There's no drug in it, so nothing interferes. Most owners keep their dog's medication going for the first 4 to 6 weeks while the barrier rebuilds, then work with their vet on reducing it.
Does your Liquid Collagen contain chicken or beef?
No. Chicken and beef are two of the most common food allergens in dogs, so putting either in an allergy product would risk making the itching worse. Our collagen is marine, sourced from wild-caught fish, with no chicken, beef, poultry or dairy. It's hypoallergenic, absorbs at up to 98%, and contains all three collagen types the skin barrier is made from.
Why do allergy medications stop working after a few weeks?
Medications suppress symptoms but don't rebuild the barrier. As it continues breaking down, symptoms return. Collagen fixes the structure, so results last.
Will this work if food changes failed?
Yes. Food changes remove trigger proteins but don't fix the broken barrier. Collagen rebuilds it so allergens stop penetrating.
Will this work for younger dogs?
Yes — and it's even more important. If your young dog is already scratching, their barrier is already damaged. Catching it early means less damage to repair, faster results, and avoiding years of expensive medications.
My dog has a sensitive stomach. Is this safe?
Yes. Our liquid formula is gentle and easy to digest. Collagen peptides and Omega 3 are both well-tolerated. Start with half dose for the first few days if concerned.
Four problems. One bottle. Hear from the people who tried everything else first.
Two years of Apoquel and she'd still wake us up at 3am clawing at her belly. Hot spots every few weeks, cone on, cone off, repeat. Tried every shampoo, every grain-free diet. Started Ryvane on a whim — within two weeks the scratching had almost completely stopped. No new hot spots since. Her skin is healing and she's sleeping through the night. So am I.
Cytopoint would work for a few weeks then we'd be straight back to the vet. The licking was constant — his paws were stained and inflamed between the toes. Three weeks on Ryvane and the licking just stopped. The staining is fading and the skin between his pads is actually healing. First time in two years.
Every two weeks it was the same cycle — brown gunk, yeast smell, pulling away when I tried to clean them. Started this collagen after two years of ear drops and vet visits. Week four I cleaned his ears and the cotton pad came back white. Three months now and not a single infection. The vet said she's never seen his ears this clean.
The foundation of healthy skin. Makes up 90% of your dog's skin tissue. Repairs damaged barrier.
Reduces the itch at its source. Clinically studied to calm immune response naturally.
The natural oils that hold the barrier together. Locks in moisture and calms redness and itch fast.
Helps the body turn collagen into new barrier tissue. Essential for the rebuild process.
Other Chews & Powders
Ryvane Liquid Collagen
Better absorption = faster results.
Chews and powders are made at high heat, destroying up to 80% of the collagen.
Liquid is cold-pressed—up to 98% gets absorbed and reaches the skin barrier.
Plus, no fighting your dog to eat a chew. Just mix into food.
Grab It While It's In Stock
Veterinarian, integrative practice
This changed how I treat allergies
I prescribed Apoquel for over a decade. It works — but dogs kept coming back needing more. When I understood the skin barrier connection, everything shifted. This formula gives dogs what medications can't — the raw material to rebuild what's broken. I've seen patients reduce medication within weeks. I recommend it to every allergy dog owner I see.
Veterinarian, small animal practice
The results surprised me
I was skeptical. Another supplement claiming to help allergies. But the science on barrier depletion is solid and the liquid absorption is real. I started recommending it to my toughest cases — dogs on maximum Apoquel still scratching. The skin improvements were visible. The coat came back. Several owners told me their dog's digestion improved too. I wasn't expecting that.
Veterinarian, dermatology focus
I wish I'd found this years ago
Most collagen supplements are underdosed chews packed with fillers. This is properly formulated — Types I, II, and III in liquid form. Dogs actually absorb it. I've had chronic allergy patients who'd tried everything show real improvement within 4-6 weeks on this. Skin calmer. Ears cleaner. Coat thicker. It's the one supplement I recommend with confidence.
Trusted by 50,000+ Pet Parents
Today, over 50,000 dogs feel the benefits of stronger skin barriers with Ryvane Liquid Collagen—finally free from chronic scratching, hot spots, and ear infections. Because we don't mask symptoms. We rebuild structure.
Your dog's skin has a protective barrier made of collagen. This barrier keeps allergens on the surface where they belong. As dogs age, they lose 7-10% of their collagen each year. When the barrier breaks down, allergens penetrate deep and trigger the immune response — that's the scratching, hot spots, and ear infections. Our liquid collagen provides the building blocks to rebuild that barrier from within.
Apoquel and Cytopoint suppress your dog's immune response to allergens. They stop the symptoms but don't fix what's causing them. Our collagen actually rebuilds the skin barrier so allergens can't penetrate as deeply in the first place. Many customers use collagen alongside their medications initially, then reduce medication over time as the barrier strengthens.
Absorption. Chews and pills contain large collagen molecules that dogs can only absorb at 20-30%. Our liquid collagen is hydrolyzed — pre-broken into tiny peptides that absorb at up to 98%. Your dog actually gets the collagen instead of passing most of it through.
Most owners notice reduced scratching within 2-3 weeks. Significant skin improvement typically happens between weeks 4-8. Full barrier rebuilding takes 8-12 weeks, which is why most customers choose multi-bottle packages.
Yes. These are natural building blocks your dog's body already uses. There's no immune suppression, no drug interactions to worry about. It's sourced from wild-caught fish and manufactured in a cGMP certified facility. Safe for long-term daily use.
Yes. Many customers start collagen while their dog is still on Apoquel or Cytopoint. As the barrier rebuilds and symptoms improve, they work with their vet to potentially reduce medications. This doesn't interfere with other treatments.
1-3ml per day based on your dog's weight. One dropper = 1ml. Instructions are on the bottle. Easy to adjust for small or large dogs.
We offer a full 60-Day Money-Back Guarantee. If you don't see real improvement in your dog's scratching, hot spots, ear infections, paw licking or coat within 60 days, simply email us and we'll happily sort out your refund. We're confident because this addresses the root cause (broken skin barrier) — not just symptoms. But if it doesn't work for your dog, you don't pay.
Yes. It's a liquid, so there are no fillers, binders or chews to break down, and it goes onto food your dog already eats. It's gentle on the gut and easy to absorb. If your dog is especially sensitive, start with half the dropper for the first few days and move up to the full amount once you see it's sitting well. A soft stool in the first day or two is rare and settles on its own.
No. Chicken and beef are two of the most common food allergens in dogs, so putting either in an allergy product would risk making the itching worse. Our collagen is marine, sourced from wild-caught fish, with no chicken, beef, poultry or dairy. It's hypoallergenic, absorbs at up to 98%, and contains all three collagen types the skin barrier is made from.
Loved by 50,000+ dog owners who’d tried everything first.
I have tried everything for my dog’s complicated skin, switching food 100x, cytopoint injections, every medication under the sun including immune system blockers. I came across this and didn’t have high hopes but figured anything is worth a shot. Let me say, I am so incredibly grateful I did order. My dog is a puppy again. Redness, constant itching, revolving ear infections, elephant skin, flaking, hair loss, it’s all resolved in 3 short months. He is 9 years old and hasn’t played in at least 3 years because he was so uncomfortable. My dog is running, playing, and happy. Trust, I read these reviews and thought they had to be paid or exaggerated. They’re not. This gave me my dog back and started helping a few days in. I am forever grateful and so is my boy. Thank you!
We also suffered with constant paw licking, hot spots, stomach upset, head shaking, and frequent ear infections. … I have been fixing her your formula for about three weeks now. Last night we all slept all night for the first time since we adopted her. She has stopped shaking her head and licking her paws. … The money back guarantee was what convinced me to try this.
The lack of scratching was the first thing I noticed. Their ears are no longer super red and inflamed inside and the head shaking is a thing of the past.
Normally my chocolate lab would get an injection in March and then possibly again in July due to the heat and allergies. He would also be taking Apoquel all summer long. I have been very happy with this product. He has not itched or had any hotspots, even with the heat and temperatures being up to 90s in Vermont.
I had tried collagen before for one of my other dogs and it didn't help him at all. However, something in me said to try this product as I read how this product is made differently from the other collagen supplements out there. I am happy to report that this is working for Sasha!
Two months in almost all his hair is back. His itching has almost stopped completely!
I purchased this product three months ago and I can't believe the difference in my Cocker baby. She is so much better. Far less scratching, her paws are clearing up, ear infections seem to have subsided. She is much happier and our household is so much calmer.
I put the collagen in his food with some broth and he eats it right up.
We started Max on this a couple months ago and truly are surprised how good his coat and skin look! He is not itching and licking like he had been. Dry skin flakes are nearly gone!
I have written a review a few days ago and can give an update Holly only licked her paws once yesterday I was always dubious about ordering online this product is amazing wish I had bought it earlier.
My girls would itch and have red, crusty, wet eyes. Since starting this formula a few months ago they both have had all of those symptoms eliminated.
Started slowly as Ruby has a sensitive gut. The delivery was taking ages so I emailed and got a reply straight away, the product arrived a few days later. So far so good, been using it for a week … I can see a difference in her coat already and last night, the first night in a long long time … NO ITCHING
I bought the 3 bottles at once and have it on auto-ship. It’s easy to get on and delay it if necessary!
Started using after trying several multivitamins that claimed to help but did nothing, after less than a week there is no scratching, licking or chewing. So very glad I found Ryvane liquid collagen, thank you so much!!
My dog nova has only been on this for 8 days and the difference I’ve seen in her already is insane! She’s a 7 year old pittie with terrible allergies & we’ve tried everything. Within days she is back to playing like a puppy again and her skin and coat feel super soft already. We have very high hopes to see how she continues to improve as it builds her skin barrier back up!
We tried this, and although it took a couple of months and we were starting to wonder if it would help her, it has now completely cleared up her problem. No more scratching, no more sore areas, and instead a lovely glossy coat, and a happier dog! … Each of the dogs seems to like the flavour and eats enthusiastically.
I have 2 dogs. An Australian shepherd and a lab cross. They both developed an itch from a flea infestation which did not go away. … I am on the second set of bottles and the itching has almost completely stopped. Thank you. It does work.
I struggled with both of my goldendoodles with scratching, hot spots, red ears, rash on their skin. … I will say their fur is so much softer and their scratching and hot spots and break outs are 90% better. … I just went to the vet for check ups on them and he said whatever you’re doing keep doing it because it’s working. It does cost me more for everything I’m doing but it’s worth every dime to see them happy and healthy!
What an amazing product. We tried everything for our boys skin problems he would never fully heal. Two weeks on this product and his skin is perfect and his fur is thick and healthy too.
This is amazing stuff, been on Apoquel for several years which helped but still scratching lots and red inflammation … delivery a bit slow too but it's well worth the wait as my furbabie is so much better … otherwise 5 stars, highly recommend
I use the Ryvane for three months. The vet said that it would take a long time for all the black pigment to go away if it ever did. But almost all of it is gone. I’m not sure what worked or if it was a combination of all of them.
My dogs have been on Apoquel, Cytopoint, Benadryl, etc. for YEARS. After using the collagen for only a month they are off all medications, all hair has grown back, paw licking is at a minimum, and they are so much happier. This product has been a savior for us. We are so thankful.
I started this 18 days ago and am seeing improvement in both my dogs. When I scratch their backs, they are no longer digging with their back leg to help.
I tried everything to get my girl to stop scratching and after about a week and a half of using this the scratching was minimal. After a month scratching was GONE.
I was worried she wouldn’t take it but she literally licks the bowl clean lol. Her paws were raw from licking and now they’re completely healed. My vet even noticed and asked what I changed.
First spring in years without constant scratching. Still itches a bit on bad pollen days but nothing like before.
I have 2 dogs, both with allergies. Started both on this at the same time. The younger one improved faster, like week 2. The older one took about 5 weeks but now they’re both so much better.
